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HIV Grand Rounds UPenn Archive

 

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Content Links: 

Series Overview  
Target Audience
Commercial Support Acknowledgement
Learning Objectives for the Series 
Course Directors
Faculty
Obtaining CME Credit for Archived Sessions: Important Information
Archived Session Topics and Speakers
Hardware/Software Notice
Accreditation Statement/Credit Designation Statement
Disclosures
Disclosure of Unlabeled Use
Disclaimer
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Series Overview: 

The Perelman School of Medicine at the University of Pennsylvania and ViralEd are proud to announce the extension of this ground-breaking CME activity. Mirroring academic grand rounds programs, these CME-certified sessions combine traditional academic grand rounds with the innovation and convenience of telemedicine. The "HIV Grand Rounds from the Perelman School of Medicine at the University of Pennsylvania" is delivered live via the Internet weekly and archived for on-demand viewing twenty-four hours after each live broadcast.

Presentations cover the most important and current topics in HIV/AIDS and are delivered by the top experts in the field. They are designed to be immediately relevant to practicing HIV clinicians and many are case-based. The final 10 minutes of each one-hour activity consists of a question and answer period. These weekly grand rounds are intended to provide clinicians with convenient and easily accessible knowledge and clinical skills they need to provide the best medical care for their HIV-positive patients.

Each session may be broadcast via your Internet connection in your conference room or auditorium for large groups to view, or individually to your personal computer at your convenience. Simply register at www.viraled.com/grandrounds for easy access.  

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Target Audience: 

This educational activity is designed for HIV specialists, Infectious Disease specialists, Internal Medicine specialists, Family Practice physicians, Dermatologists, Osteo-specialists, Nephrologists, Hematology/oncologist, Psychiatrists, Public Health professionals, OB/GYN physicians and other clinicians interested and involved in the care of patients with HIV/AIDS.

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Commercial Support Acknowledgement: 

These activities are supported by educational grants from Gilead Sciences and Janssen Therapeutics.  

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Learning Objectives for the Series: 

Upon completion of the educational activity participants should be able to:

  • List the important factors that play a role in ARV therapy success;
  • Explain the role that drug adverse events, drug pharmacokinetics and patient adherence play in achieving ARV success and avoiding morbidity and mortality; 
  • Describe the important opportunistic infections and co-morbidities that may affect HIV-positive patients and increase their risk for morbidity and mortality;
  • Discuss the importance of individualizing the care of each HIV-positive patient.
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Course Directors: 

JohnBartlett 

John Bartlett, MD
Professor of Medicine,
Johns Hopkins School of Medicine
Baltimore, Maryland 

CalvinCohen  Calvin J. Cohen, MD, MS
Research Director,
CRI New England
Clinical Instructor,
Harvard Medical School
Boston, Massachusetts   
 Ian Frank Ian Frank, MD
Professor of Medicine,
Director, Antiretroviral Clinical Research
University of Pennsylvania
Philadelphia, Pennsylvania
   
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Faculty: 


Jay Kostman, MD
Clinical Associate Professor of Medicine
Division of Infectious Diseases
Chief, Infectious Diseases Division,
Penn Presbyterian Medical Center
University of Pennsylvania
Philadelphia, Pennsylvania

  K. Rajender Reddy, MD
  Professor of Medicine,
  Professor of Medicine in Surgery,
  Director of Hepatology,
  Medical Director of Liver Transplantation
  University of Pennsylvania School of Medicine
  Philadelphia, Pennsylvania

Vincent Lo Re, III, MD
Clinical Associate Professor of Medicine,
Division of Infectious Diseases
Penn Presbyterian Medical Center
University of Pennsylvania
Philadelphia, Pennsylvania

  Robert Siliciano, MD, PhD
  Professor of Medicine,
  Molecular Biology and Genetics,
  Howard Hughes Medical Institute
  Johns Hopkins University School of Medicine
  Baltimore, Maryland

Priscilla Hsue, MD
Associate Professor of Medicine,
Division of Cardiology
University of California, San Francisco
School of Medicine
San Francisco, California

  Louis J. Picker, MD
  Associate Director,
  Vaccine and Gene Therapy Institute
  Head, Pathobiology and Immunology Division
  Oregon Health and Science University
  Portland, Oregon

Timothy Wilkin, MD, MPH
Associate Professor of Medicine,
Division of Infectious Diseases
Weill Medical College of Cornell University
New York, New York




  David Wohl, MD
  Associate Professor of Medicine,
  Division of Infectious Diseases, School of Medicine,
  The University of North Carolina, Chapel Hill, North Carolina
  Co-Director of HIV Services for the North Carolina
  Department of Corrections
  Chapel Hill, North Carolina 

Steven G. Deeks, MD
Professor of Medicine,
University of California, San Francisco
San Francisco, California

  Pablo Tebas, MD
  Professor of Medicine
  University of Pennsylvania
  Philadelphia, Pennsylvania

Todd Barton, MD
Associate Professor of Medicine,
The Perelman School of Medicine at the University of Pennsylvania 
Philadelphia, Pennsylvania



  Ian McGowan MD
  Professor of Medicine,
  Division of Gastroenterology, Hepatology and Nutrition
  University of Pittsburgh School of Medicine
  Pittsburgh, Pennsylvania



Chloe L. Thio, MD
Professor of Medicine,
Division of Infectious Diseases
John Hopkins University
Baltimore, Maryland

  Renslow Sherer, MD
  Professor of Medicine,
  Section of Infectious Diseases and Global Health,
  University of Chicago
  Chicago, Illinois

Charles Hicks, MD
Professor of Medicine
Department of Infectious Diseases
Duke University Medical Center
Durham, North Carolina

  Beatrice Hahn, MD
  Professor of Medicine and Microbiology
  University of Pennsylvania
  Philadelphia, Pennsylvania



Robert M. Grant, MD, MPH
Betty Jean and Hiro Ogawa Endowed Investigator
Gladstone Institute of Virology and Immunology
Associate Professor of Medicine
University of California, San Francisco
San Francisco, California

  George M. Shaw, MD PhD
  Professor of Medicine
  Division of Hematology / Oncology
  University of Pennsylvania 
  Philadelphia, Pennsylvania



Robert Gross, MD, MSCE
Associate Professor of Medicine
Infectious Diseases Division
Associate Professor of Epidemiology
Department of Biostatistics and Epidemiology
University of Pennsylvania Perelman School of Medicine
Philadelphia, Pennsylvania

  Doreen Ramogola-Masire, MD
  Country Director and Lead Physician Women's Health
  Botswana UPenn Partnership
  Gaborone, Botswana





James D. Neaton, PhD
Professor of Biostatistics
University of Minnesota School of Public Health
Minneapolis, Minnesota



  Una O'Doherty MD PhD
  Associate Professor of Pathology
  and Laboratory Medicine
  The Hospital of the University of Pennsylvania
  Philadelphia, Pennsylvania

Michel C. Nussenzweig PhD
Sherman Fairchild Professor
Rockefeller University
Investigator, HHMI laboratory of Molecular Immunology
New York, New York


  Valerianna Amorosa MD
  Chief of Infectious Diseases, VAMC Assistant Professor
  of Clinical Medicine
  The Perelman SOM at the University of Pennsylvania
  Philadelphia, Pennsylvania

Michael R. Betts, PhD
Assistant Professor
Department of Microbiology
Perelman School of Medicine
University of Pennsylvania







  Chris Beyrer MD MPH
 
Professor
  Director, Johns Hopkins Fogarty AIDS International
  Training and Research Program
  Director, Johns Hopkins Center for Public health
  and Human Rights
  Senior Scientific Liaison, HIV Vaccine Trials Network
  Associate Director of Public Health, Johns Hopkins Center for
  Public Health
  Baltimore, Maryland

Daniel Kuritzkes MD
Chief, Division of Infectious Diseases
Brigham and Women's Hospital
Professor of Medicine, Harvard Medical School
Boston, Massachusetts

  Thomas Coyne MD PhD
  Department of Pathology
  Hospital of the University of Pennsylvania
  Philadelphia, Pennsylvania



Jeffrey Hafkin MD
Fellow, Infectious Diseases
Perelman School of Medicine at the University of Pennsylvania
Philadelphia, Pennsylvania 


  Amy Pruitt MD
  Associate Professor of Neurology
  Hospital at the University of Pennsylvania
  Philadelphia, Pennsylvania

Ronald L. Wolf MD PhD
Associate Professor of Radiology
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania






Corey Casper MD MPH
Associate Member, Vaccine and Infectious Disease, Public Health Science and Clinical Research Divisions
Fred Hutchinson Cancer Research Center
Associate Professor of Medicine, Epidemiology and Global Health University of Washington
Medical Director of Infection Control, Seattle Cancer Care Alliance
Seattle, Washington

Marshall J. Glesby MD PhD
Associate Professor of Medicine and
Associate Professor of Public Health 
Weill Cornell Medical College
Associate attending Physician 
New York-Presbyterian Hospital
New York, New York

David M. Margolis, M.D.
Professor of Medicine, Microbiology and Immunology,
Epidemiology
Director, Program in Translational Clinical Research
IGHID
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina

Peter W. Hunt MD
Assistant Professor in Residence
University of California, San Francisco
San Francisco, California



Domenico Mavilio, MD, PhD
Group Leader,
Clinical and Experimental Immunology
Instituto Clinico Humanitas
Rozzano, Milano Italy

Luis Montaner DVM MSc DPhil
Wistar Institute Professor of Medicine
Director, HIV-1 Immunopathogenesis Laboratory
The Wistar Institute
Philadelphia, Pennsylvania



Paul E. Sax MD
Clinical Director, Division of Infectious Diseases
Brigham and Women's Hospital
Associate Professor of Medicine
Harvard Medical School
Boston, Massachusetts
 
Roy M. Gulick MD
Chief of the Division of Infectious Diseases
Professor of Medicine
Weill Medical College
Cornell University
New York, New York
 
Lawrence Corey MD
President and Director
Fred Hutchinson Cancer Research Center
Professor, Medicine and Laboratory Medicine
University of Washington
Seattle, Washington

Vincent Lo Re III MD
Clinical Associate Professor of Medicine,
Division of Infectious Diseases
Penn Presbyterian Medical Center
Perelman School of Medicine at the University of Pennsylvania
Philadelphia, Pennsylvania

Jay R. Kostman MD
Clinical Associate Professor of Medicine
Division of Infectious Diseases
Chief, Infectious Diseases Division,
Penn Presbyterian Medical Center
Philadelphia, Pennsylvania
 
Mark Sulkowski MD
Associate Professor of Medicine and 
Medical Director, Viral Hepatitis Center
John Hopkins University School of Medicine
Baltimore, Maryland
 
Myron S. Cohen MD
J. Herbert Bate Professor
Medicine, Microbiology and Immunology and Epidemiology
The University of North Carolina at Chapel Hill
Chapel Hill, North Carolina

Obtaining CME Credit for Archived Sessions: Important Information  

  • This section pertains only to those who would like CME credit. If you do not want CME credit, please proceed to the next section below.

  • The Perelman School of Medicine at the University of Pennsylvania provides credit for all archived sessions in this educational activity.
  • If CME credit is desired for any of these sessions, proceed to http://penncmeonline.com/user/register to create your personal CME account, or if you already have an account, click the "Yes, I want CME credit" button below. You will be redirected to their website.
  • After your personal CME account is established this one time, you will receive an email with your initial login information. Follow the link in the email to change your password and complete the one-time profile set up. Additional instructions may be found at http://penncmeonline.com/user_guides.
  • A complete listing of all archived sessions, as listed below in the next section, can be found on the UPenn CME website. Follow the "Yes, I want CME Credit" button below to view the selections and earn CME credit. 

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After clicking this button a new window will open and you will be redirected to the University of Pennsylvania Office of CME website for this activity.

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Archived Session Topics and Speakers:

ATTENTION: After selecting a session to view you will be taken to a short form. If you have logged on to ViralEd.com the form will be prepopulated where only one question, related to the number of participants, is left blank. Once this short form has been filled out and the "Go To Program" button has been pressed you will be taken directly to the program, which will commence immediately.


















November 3rd, 2011
Speaker: Michel C. Nussenzweig, MD, PhD
Topic: Human Antibody Response Against HIV


November 17th, 2011
Speaker: K. Rajender Reddy, MD
Topic: An Update from the 62nd AASLD Conference in San Francisco, CA


January 12th, 2012
Speaker:  Reuben S. Harris  PhD
Topic: The Feasibility of Modulating Cellular DNA Mutating Enzymes as Next-generation HIV/AIDS Therapeutics


January 19th, 2012
Speaker:  Daniel R. Kuritzkes
 MD
Topic:  Clinical Signifacance of HIV-1 Drug-resistant Minority Variants 


January 26th, 2012
Speakers:  Ian Frank MD; Thomas Coyne MD PhD; Jeffrey Hafkin MD; Amy Pruitt MD; Ronald L. Wolf MD PhD

Topic:  Real Cases from the Hospital of the University of Pennsylvania


February 2nd, 2012
Speaker:   Corey Casper MD MPH

Topic:    The Spectrum and Pathogenesis of HIV-associated Malignancies in Resource-limited Settings


February 9th, 2012
Speaker:  Marshall J. Glesby MD PhD

Topic: Update on the Cardiovascular Complications of HIV Infection 


February 16th, 2012
Speaker:    David M. Margolis MD

Topic:  Strategies to Cure HIV Infection 


February 23rd, 2012
Speaker: Peter W. Hunt MD

Topic: Inflammation and HIV Infection:  A Paradigm Shift in the Management of HIV Disease 

 

March 1st, 2012
Speakers: Ian Frank MD, Todd Barton MD & Valerianna Amorosa MD

Topic: Real Cases from the Hospital of the University of Pennsylvania: "Preventable" Lung Disease in HIV Infected Patients

 

March 15th, 2012
Speaker: Domenico Mavilio, MD, PhD
Topic: Natural Cytotoxicity Receptors: New Insights on Their Role in the Context of g/d T-cell Responses

 

March 22nd, 2012
Speaker: Ian Frank MD

Topic: Highlights from the 19th Conference on Retroviruses and Opportunistic Infections

 

March 29nd, 2012
Speaker:  Luis Montaner DMV MSc DPhil 

Topic: HIV Control Mediated by Interferon-alpha Immunotherapy


April 5th, 2012
Speaker:  Paul E. Sax MD

TopicContemporary Issues in the Management of Treatment-Experienced Patients


April 12th, 2012
Speaker:  Roy M. Gulick  MD MPH 

Topic: Art Controversies 2012

 

April 19th, 2012
Speaker:  Lawrence Corey MD

Topic:   Control of HSV Infection:  The Action is in the Mucosa

 

April 26th, 2012
Speaker:  Vincent Lo Re MD & Jay Kostman MD

Topic:  Case Studies from the Hospital at the University of Pennsylvania


May 3rd, 2012
Speaker:   Mark Sulkowski MD

Topic:  An Update from the Annual Meeting of the European Association for the Study of the Liver 

 

May 9th, 2012
Speaker: Myron S. Cohen  MD

Topic: Prevention of HIV-1 Infection

 Twenty-four hours after each live broadcast, the session will be available for on-line viewing for one year.
The 26 one-hour pilot program lectures that ran from September 29, 2010 - May 4, 2011 are available for viewing and CME credit. Follow the button below to view these activities.
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ATTENTION: After selecting a session to view you will be taken to a short form. If you have logged on to ViralEd.com the form will be prepopulated where only one question, related to the number of participants, is left blank. Once this short form has been filled out and the "Go To Program" button has been pressed you will be taken directly to the program, which will commence immediately.
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Hardware/Software Notice: 

You will need Internet to participate in this activity.

Accreditation Statement: 

This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the Perelman School of Medicine at the University of Pennsylvania and ViralEd, LLC. The Perelman School of Medicine at the University of Pennsylvania is accredited by the ACCME to provide continuing medical education for physicians.
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Credit Designation Statement: 

The Perelman School of Medicine at the University of Pennsylvania designates each enduring material for a maximum of 1 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
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Disclosures: 

It is policy at the Perelman School of Medicine at the University of Pennsylvania and ViralEd, LLC for individuals who are in a position to control the content of an educational activity to disclose to the learners all relevant financial relationships that they have with any commercial interest that provides products or services that may be relevant to the content of this continuing medical education activity. For this purpose we consider relationships of the person involved in the CME activity to include financial relationships of a spouse or partner.
The intent of this policy is not to prevent expert faculty with relevant relationship(s) with commercial interest(s) from involvement in CME, but rather to ensure that Penn CME-certified activities promote quality and safety, are effective in improving medical practice, are based on valid content, and are independent of control from commercial interests and free of commercial bias. Peer review of all content was conducted for all faculty presentations whose disclosure information provided to the Penn Office of CME was found to contain relationships that created a conflict of interest relative to the topic of their presentation. In addition, all faculty were instructed to provide balanced, scientifically rigorous and evidence-based presentations.
The staff in the Office of CME at the Perelman School of Medicine at the University of Pennsylvania (Rodman Campbell, Mila Kostic, Belinda Rose, and Mindy Pollock Troy), our educational partner ViralEd, LLC (Richard Gordon, Brian Boyle, MD, JD and Ed Hettman), and the peer reviewer, Zalman Agus, MD, Associate Dean for Continuing Medical Education, have reported that they have no relevant financial relationships with any commercial interests related to the content of this educational activity.
The following faculty or planning committee members have disclosed that they have no relevant financial relationships with any commercial interests related to the content of this educational activity:

John Bartlett, MD



Jay Kostman, MD



Robert Siliciano, MD



Todd Barton, MD



Chloe L. Thio, MD



Geroge M. Shaw, MD PhD



Doreen Ramogola-Masire, MD



James D. Neaton, PhD



Michel C. Nussenzweig, MD PhD



Valeriana Amorosa, MD



Chris Beyrer MD MPH



Reuben S. Harris PhD



Ian McGowan, MD



Una O'Doherty MD PhD



Thomas Coyne MD PhD



 Jeffrey Hafkin MD



Amy Pruitt MD



 Ronald L. Wolf MD PhD



Corey Casper MD MPH



Myrone S. Cohen


       
The following faculty or planning committee members have reported the listed relevant financial relationships with commercial interests related to the content of this educational activity:

Name

Commercial Supporter

Relationship




Calvin Cohen, MD

Gilead; Bristol-Myers Squibb; Merck & Co.; Tibotec; ViiV

Contracted Research

 

Gilead; Bristol-Myers Squibb; Merck & Co.; Tibotec; Abbott

Consulting Fees

 

Gilead; Bristol-Myers Squibb; Merck & Co.; Tibotec

Speakers Bureaus

 
 
 
 

Ian Frank, MD

GlaxoSmithKline

Contracted Research

 

Gilead

Consulting Fees

 
 
 

Vincent Lo Re, III, MD

AstraZeneca, Bristol-Myers Squibb

Contracted Research




K. Rajender Reddy, MD

Gilead, Merck, Tibotec, Vertex

Advisory Board 

 

Boehringer-Ingelheim, Bristol-Myers Squibb, Merck, Tibotec, Vertex

Contracted Research

 
 
 

Priscilla Hsue, MD

Bristol-Myers Squibb, Gilead

Speakers Bureau

 
 
 

Louis Picker, MD       

CMV Vector Technology

Contracted Research

 
 
 

Timothy Wilkin, MD

 

GlaxoSmithKline

Contracted Research

 
 
 

David Wohl, MD

Merck & Co.; GlaxoSmithKline   

Contracted Research

 

Tibotec; Gilead; Bristol-Myers Squibb; Abbott

Consulting Fees

 
 
 

Steven Deeks, MD 

Merck & Co.; Gilead Sciences

Contracted Research

 

Tobira; ViiV

Consulting Fees

 
 
 

Pablo Tebas, MD

GlaxoSmithKline 

Adjudication Committee

 

Cytheris

DSMB Committee

 

GlaxoSmithKline; BMS; Gilead; Pfizer; Vertex; Inovio

Contracted Research

 
 
 

Renslow Sherer, MD  

BMS

Grant Support for Research

 

Abbott

Grant Support for Research

 

Gilead

Advisory Board with Honoraria  

 

Abbott

Advisory Board with Honoraria

 
 
 

Robert M. Grant

      

Gilead - Donation of study drug for NIH funded research

Investigator

 
 
 

Robert Gross, MD, MSCE

BMS

Research Investigator

 
 
 
Daniel R. Kuritzkes MD Abbott, BSC, Boehringer-Ingelheim, Gilead, Merck, Roche & ViiV

Consultant

  Gilead & Merclk Principal Investigator
  Roche Speaker
 
 
 
Marshall J. Glesby MD PhD Pfizer; SIGA Technologies Consultant
  Pfizer Clinical Trial Researcher
 
 
 
David M. Margolis MD Merck, BMS, Gilead, GSK    Research & Materials Funding
  Gilead          Common Stocki
  Merck, BMS, GSK, Chimerix, Boehringer, ViiV Consulting Honaria
  Argos, Tibotec  Clinical Trial Funding
 
 
 
Peter W. Hunt MD Merck Consultant
  Pfizer, Salix, Roche Investigator-Initiated Study
  Boehringer-Ingelheim, Gilead Speaker
 
 
 
Luis J. Montaner DVM MSc DPhil Pfizer Research Investigator
     
 
 
 
Paul E. Sax, MD Abbott, Aileron, BMS, Gilead, GSK, Merck, Tibotec Consultant
  BMS, Gilead, Merck, GSK, Tibotec Hospital Grant
     
 
 
 
Roy M. Gulick MD MPH BMS, Gilead, Janssen Ad-hoc Consultant (honorarium)
     
 
 
 
Lawrence Corey MD Immune Design Corp Stock holder; Scientific Advisory Board
     
 
 
 
Vincent Lo Re III MD  AstraZeneca, Bristol-Myers Squibb

Contracted Research

     
 
 
 
Jay Kostman MD Vertex                                                                                                                    Consultant
  Merck Consultant
     

 


 
Mark Sulkowski MD Abbott, BMS, Gilead, Janssen, Merck,Roche, Vertex, Boehringer Ingelheim Research Gra nt to John Hopkins University (PI)
  Abbott, BMS, Gilead, Janssen, Merck,Roche, Vertex, Boehringer Ingelheim Scientific Advisory Panel
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Disclosure of Unlabeled Use: 

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. ViralEd, LLC, the Perelman School of Medicine at the University of Pennsylvania, Gilead Sciences and Janssen Therapeutics do not recommend the use of any agent outside of the labeled indications. 
Product Investigational and / or Off-label Use

Amy Pruitt MD

 
methohexate, Rituxan, Tenodex
Treatment of primary CNS lymphoma
 
 
Peter W. Hunt MD  
Dr. Hunt indicated that:
His presentation will contain discussion of ongoing research studies of drugs targeting immune activation in treated HIV infection with the understanding that these developments cannot yet be recommended for clinical use as there is no evidence to support their use at this time.
 
 
Luis J. Montaner DVM MSc DPhil     
Interferon-alpha 2a (Roche/Genentech) Ind for HIV mono-infected
 
 
Roy M. Gulick MD MPH Investigational Antiretroviral Drugs (multiple)
 
 
Jay Kostman MD  
Telaprevir Co-infection
Boceprevir Co-infection


Mark Sulkowski MD Multiple experimental HCV agents
   
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of ViralEd, LLC, the Perelman School of Medicine at the University of Pennsylvania, Gilead Sciences and Janssen Therapeutics. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications and warnings.
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Disclaimer: 

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient's conditions and possible contraindications on dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities. 
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You may contact Richard Gordon by phone at 1-856-506-5790 or by email at rgordon@viraled.com for additional assistance.
For CME questions please contact the Perelman School of Medicine at the University of Pennsylvania Office of CME:  
upennCME@mail.med.upenn.edu.

We look forward to bringing the highest-quality CME directly to you.

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