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Enduring Clinical Research

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Presented By:

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About the Program

Program Overview

Some of the most important challenges facing HIV health care providers today involve understanding and utilizing the wealth of clinical research data which provide guidance in constructing first- and second-line ARV treatment regimens. Clinicians caring for HIV-positive patients need to understand the importance of selecting - and have the ability and knowledge to select - an ARV regimen that maximizes the patient's chance for long-term success and minimizes the risk of adverse events, morbidity and mortality. This requires that the clinician have (1) a familiarity with the clinical research and other data that have evaluated ARV efficacy and other factors that should be involved in ARV selection and (2) an ability to assess the needs and abilities of the individual patient so that ARV therapy can be appropriately individualized. This program will educate clinicians regarding the clinical research and other data that should be considered when planning and deciding on ARV therapy so that all patients receive the ARV therapy that is most likely to be successful for them.

This tuition-free program is for health care providers who treat HIV-positive patients and there are no prerequisites.

Commercial Support Acknowledgement

This activity is supported by an educational grant from Tibotec Therapeutics. 

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Learning Objectives and Program Details

After completing this activity, the participant will demonstrate the ability to:

  1. Identify appropriate approach(s) to use in gathering information from the patient and choose an appropriate, individualized ARV regimen that maximizes the chance of virologic success.

  2. Implement evidence-based methods for improving patient adherence to ARV therapy and providing an ARV regimen with forgiving pharmacokinetics into your clinical practice.

  3. Apply important factors that play a role in ARV therapy success in your clinical practice.

  4. Apply the clinical research studies comparing various ARV therapy regimens and strategies into your practice.

The Johns Hopkins University School of Medicine takes responsibility for the content, quality, and scientific integrity of this CME activity.
Release Date: January 26, 2010
Expiration Date: January 25, 2011

Estimated time to complete this activity: 2 hours

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Intended Audience

This activity is intended for physicians, physicians' assistants, advanced practice nurses, and other healthcare professionals involved in the treatment and management of patients with HIV infection. There are no prerequisites.

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Accreditation Statement

The Johns Hopkins University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

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Credit Designation Statement

The Johns Hopkins University School of Medicine designates this educational activity for a maximum of 2.0 AMA PRA Category 1 Credits™.  Physicians should only claim credit commensurate with the extent of their participation in the activity.

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Course Directors

John Bartlett, MD
Professor of Medicine,
Johns Hopkins School of Medicine
Baltimore, Maryland
...
Calvin J. Cohen, MD, MS
Research Director,
CRI New England
Clinical Instructor,
Harvard Medical School
Boston, Massachusetts

Faculty

Edwin DeJesus, MD
Medical Director,
Orlando Immunology Center
Orlando, Florida
  Ian Frank, MD
Professor of Medicine,
Director, Antiretroviral Clinical Research
University of Pennsylvania
Philadelphia, Pennsylvania

Luther A. Virgil, Jr., MD
hief Medical Officer,
National Minority Clinical Research Association(NMCRA)
Fairfield, New Jersey
   

Full Disclosure Policy Affecting CME Activities

As a provider accredited by the Accreditation Council for Continuing Medical Education (ACCME), it is the policy of the Johns Hopkins University School of Medicine to require the disclosure of the existence of any relevant financial interest or any other relationship a faculty member or a sponsor has with the manufacturer(s) of any commercial product(s) discussed in an educational presentation. The presenting faculty reported the following:

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Faculty Financial Disclosures

John Bartlett, MD:
  • Grants/Research Support: Johnson & Johson, Abbott International, Pfizer, Salient, Optimer
  • Consultant/Advisory Board:  Johnson & Johnson, Optimer,  Salient
  • Honoraria:  Abbott International, Pfizer 
Calvin Cohen, MD, MS:
  • Consulting Agreements: Gilead, Bristol Myers Squibb, Merck, Tibotec
  • Honorarium: Gilead, Bristol Myers Squibb, Merck, Tibotec
  • Speakers Bureau: Gilead, Bristol Myers Squibb, Merck, Tibotec
Edwin DeJesus, MD:
  • Sources of Funding for Research: Abbott Laboratories, Achillion, Avexa, Boehringer Ingelheim, Bristol Myers Squibb, Gilead Sciences, GlaxoSmithKline, Hoffman LaRoche Laboratories, Merck, Pfizer, Schering Plough, Taimed, Tobira, Tibotec, Vertex
  • Consultant/Honorarium: Bristol Myers Squibb, Gilead Sciences, GlaxoSmithKline, Merck, Tibotec, Vertex Pharmaceuticals
  • Speakers' Bureau: Gilead Sciences, Merck, Tibotec, Virco.
Ian Frank, MD:
  • Grants/Research Support: Merck 
  • Consulting Agreements/Honoraria: Abbott; Bristol-Myers Squibb; Gilead Sciences; GlaxoSmithKline; Merck, Tibotec
  • Speakers' Bureau: Bristol-Myers Squibb; Gilead Sciences; Tibotec.
Luther Virgil, MD:
  • Indicated that he  receives no commercial support or financial interest relevant to this activity.

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Off-label Product Discussion

Drs. Bartlett, Cohen, DeJesus, Frank and Virgil have disclosed that their presentation will reference unlabelled/unapproved uses of the following products: efavirenz, maraviroc, and etravirine.

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Method to Participate and Obtain Continuting Medical Education Credit

In order to receive credit, participants must view the entire activity and complete a post test and activity evaluation online. Upon a successful score of 70% on the post test and completion of the evaluation, participants may print out their certificate. Participants may access the program, post test and evaluation for this activity by clicking the link below:

Clinical_Research_ Launch_Online_Button

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Request for Program Slides and Review 

To request a copy of the program slides as well as further education on how to use the slides please Click Here to fill out a content request form.



Opinions and recommendations expressed by faculty and other experts whose input is included in this program are their own. This enduring material is produced for educational purposes only. Use of Johns Hopkins University School of Medicine name implies review of educational format design and approach. Please review the complete prescribing information of specific drugs or combination of drugs, including indications, contraindications, warnings and adverse effects before administering pharmacologic therapy to patients.

The Office of Continuing Medical Education (CME) at the Johns Hopkins University School of Medicine is committed to protect the privacy of its members and customers. Johns Hopkins University SOM CME maintains its Internet site as an information resource and service for physicians, other health professionals and the public. Continuing Medical Education at the Johns Hopkins University School of Medicine will keep your personal and credit information confidential when you participate in a CME Internet based program. Your information will never be given to anyone outside of the Johns Hopkins University School of Medicine’s CME program. CME collects only the information necessary to provide you with the services that you request.

Copyright © 2008 The Johns Hopkins University School of Medicine. All rights reserved.

 

 

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