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Jointly Sponsored by: The Perelman School of Medicine at the University of Pennsylvania,
The Penn Cener for AIDS Research and ViralEd, Inc.
 
UPenn CME - 2019          UPenn CFAR           VE Logo 2019
 
 
 
Presenters: Michael Nonnemacher, PhD
  
Date/Time: Thursday, April 21, 2022 at 12:00 PM EDT
 
Topic: Design insights for gene-editing a cure for HIV
 
  
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SERIES OVERVIEW:

The Perelman School of Medicine at the University of Pennsylvania and ViralEd are proud to announce the extension of this ground-breaking CME activity. Mirroring academic grand rounds programs, these CME-certified sessions combine traditional academic grand rounds with the innovation and convenience of telemedicine. The "HIV Grand Rounds from the Perelman School of Medicine at the University of Pennsylvania" is delivered live via the Internet every Thursday at 12:00pm Eastern Time and is available for on-demand viewing immediately following the live broadcast.

Presentations cover the most important and current topics in HIV/AIDS and are delivered by the top experts in the field. They are designed to be immediately relevant to practicing HIV clinicians and many are case-based. The final 10 minutes of each one-hour educational activity consists of a live question and answer period, with the presenting faculty member available to answer questions asked by attendees using the webinar interface. These weekly grand rounds are intended to provide clinicians with convenient and easily accessible knowledge and clinical skills they need to provide the best medical care for their HIV-positive patients.

Each session may be broadcast via your Internet connection individually to your personal computer at your convenience. Simply register at www.viraled.com/hivgrandrounds for easy access.

TARGET AUDIENCE:

This program has been designed for Family Medicine, Pediatrics, Neurology, Psychiatry, Internal Medicine, Internal Medicine - Infectious Disease.

ACKNOWLEDGEMENT OF COMMERCIAL SUPPORT:

Gilead Sciences Medical Affairs, Janssen Therapeutics, ViiV Healthcare, and Merck Sharp & Dohme Corp.

SERIES EDUCATIONAL OBJECTIVES:

After participating in this regularly scheduled series, participants should be able to:

  • Apply in clinical practice approaches for preventing HIV infection and getting newly diagnosed patients rapidly into care
  • Individualize ARV therapy for the treatment-naïve and treatment-experienced patients to support adherence and patient satisfaction
  • Manage various patient populations, such as the aging patient with HIV infection, including issues associated with cardiovascular and bone disease, PWIDs, and underserved populations
  • Understand the basic science concepts involved with HIV and be able to apply those concepts to HIV therapeutics, epidemiology, and other issues involved in HIV patient care and HIV prevention

SESSION EDUCATIONAL OBJECTIVES:

After participating in this regularly scheduled series, participants should be able to:

  • Describe how CRISPR gene editing works in general and for HIV
  • Discuss how genetic variation of HIV within and between people with HIV impacts gene-editing design (gRNA, Cas selection)
  • Compare and contrast how epigenetics and cell activation state impacts on and off-target effects of CRISPR gene-editing

PROGRAM FACULTY:
 

  Nonnemacher, Mike
Michael Nonnemacher, PhD
Professor of Microbiology & Immunology
Drexel University College of Medicine
Philadelphia, Pennsylvania



 

ACCREDITATION:

In support of improving patient care, Penn Medicine is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

DESIGNATION OF CREDIT:

Physicians: Penn Medicine designates this live activity for a maximum of 1.00 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurses/Pharmacists: This activity is not approved for nursing or pharmacy contact hours

PAs: AAPA accepts certificates of participation for educational activities certified for AMA PRA Category 1 CreditTM from organizations accredited by ACCME or a recognized state medical society. PAs may receive a maximum of 1.00 Category 1 credits for completing this activity.

DISCLOSURE OF RELEVANT FINANCIAL RELATIONSHIPS AND UNAPPROVED USES OF PRODUCTS:

It is policy at Penn Medicine Office of Continuing Medical and Interprofessional Education for individuals who are in a position to control the content of an educational activity to disclose to the learners all relevant financial relationships that they have with any commercial interest that provide products or services that may be relevant to the content of this continuing education activity.  For this purpose, we consider relationships of the person involved to include financial relationships of a spouse or partner.

The intent of this policy is to ensure that Penn CME/CE certified activities promote quality and safety, are effective in improving medical practice, are based on valid content, and are independent of control from commercial interests and free of commercial bias. Peer review of all content was conducted for all faculty presentations whose disclosure information was found to contain relationships that created a conflict of interest relevant to the topic of their presentation. In addition, all faculty were instructed to provide balanced, scientifically rigorous and evidence-based presentations.

The staff in the Office of Continuing Medical and Interprofessional Education (CME and IPCE)  have disclosed that they have no relevant financial relationships with any commercial interests related to the content of this educational activity. Any peer reviewer with a potential conflict of interest will recuse themselves from the peer review process.

The following faculty or planning committee members have disclosed that they have no relevant financial relationships with any commercial interests related to the content of this educational activity:

  • ViralEd, Inc: Brian Boyle; Oliver Fultz; Rick Gordon
  • Presenter: Michael Nonnemacher, PhD

The following faculty or planning committee members have reported the listed relevant financial relationships with commercial interests related to the content of this educational activity:

  •  Ian Frank, MD (Program Co-Director)
    • Advisor/Review Panel Member: Gilead Sciences; GlaxoSmithKline
    • Consultant: Merck
    • Grants/Research Support: Johnson and Johnson; Moderna; Sanofi Pasteur
    Katherine Bar, MD (Program Co-Director)
    • Consulting Fee: Abbvie (Relationship ended)

Relevant financial relationships are those relationships in which the individual benefits by receiving a salary, royalty, intellectual property rights, consulting fee, honoraria, ownership interest (e.g., stocks, stock options or other ownership interest, excluding diversified mutual funds), or other financial benefit. Financial benefits are usually associated with roles such as employment, management position, independent contractor (including contracted research), consulting, speaking and teaching, membership on advisory committees or review panels, board membership, and other activities from which remuneration is received or expected.

DISCLOSURE OF UNAPPROVED USES OF PRODUCTS:

  • Michael Nonnemacher, PhD: None.
 
VIEW PROGRAM:
HIV Grand Rounds from the Perelman School of Medicine at the University of Pennsylvania: Thursday, April 21, 2022
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